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通过统计分析对人类卵巢中的微量元素数据进行生物学评估。

Biological evaluation of trace element data in human ovaries by statistical analysis.

作者信息

Kanias G D, Kouri E

机构信息

Radioanalytical Laboratory, Institute of Physical Chemistry, N.C.S.R. "DEMOKRITOS." Aghia Parakevi Attikis, Athens 153 10, Greece.

出版信息

Biol Trace Elem Res. 1996 Apr;52(1):65-116. doi: 10.1007/BF02784090.

DOI:10.1007/BF02784090
PMID:9156540
Abstract

Analysis of variance, analysis of covariance, correlation coefficient, multiple correlation, and partial correlation coefficient statistical tests were applied to Cs, Cr, Co, Fe, Rb, Sc, Se, and Zn content in human ovaries in order to evaluate statistically the possible relationships between these trace elements at: the ovary as an organ, each ovarian phase separately, each morphological part independent of the ovarian phase, and between cortex and medulla within the ovarian phases. The element Cs seems to have a homogeneous distribution between cortex and medulla within reproductive and menopausal phase. Zinc shows a trend to have an antagonistic relation with Cs, Cr, Co, and Fe during fetal and reproductive phases and not during menopausal phase. The relationship between Zn and Cs when Fe is kept constant could be used as a tool for the decontamination of the ovary from an abnormal Cs content or for the inhibition of the accumulation of the same element to the ovarian tissue.

摘要

为了从统计学角度评估这些微量元素在以下方面的可能关系,我们对人卵巢中的铯(Cs)、铬(Cr)、钴(Co)、铁(Fe)、铷(Rb)、钪(Sc)、硒(Se)和锌(Zn)含量进行了方差分析、协方差分析、相关系数分析、复相关分析和偏相关系数统计检验:作为一个器官的卵巢、各个单独的卵巢期、独立于卵巢期的每个形态部分,以及卵巢期内的皮质和髓质之间。元素铯在生殖期和绝经期的皮质和髓质之间似乎具有均匀分布。锌在胎儿期和生殖期显示出与铯、铬、钴和铁存在拮抗关系的趋势,而在绝经期则不然。当铁保持恒定时,锌与铯之间的关系可作为一种工具,用于清除卵巢中异常的铯含量或抑制同一元素在卵巢组织中的积累。

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本文引用的文献

1
Discriminant analysis of trace element distribution in normal and malignant human tissues.
Cancer Res. 1989 Aug 1;49(15):4210-5.