Liu Y, Menold E, Dullenkopf A, Reissnecker S, Lormes W, Lehmann M, Steinacker J M
Abt. Sport- und Leistungsmedizin, University of Ulm, Germany.
Clin Physiol. 1997 Mar;17(2):171-82. doi: 10.1046/j.1365-2281.1997.02323.x.
The use of the acetylene rebreathing method to estimate cardiac output (CO) during high-intensity exercise, which may be influenced by recirculation of acetylene, has not been validated. This study was designed to validate the acetylene rebreathing method to measure CO during high-intensity exercise using the direct Fick method. CO was measured at rest and during exercise at 25%, 50%, 75% and 90% of the nine subjects' maximum oxygen uptake (VO2max) by the direct Fick and acetylene rebreathing method. CO measured by the acetylene rebreathing method correlated with work rate (r = 0.90, P < 0.01) and with oxygen uptake (r = 0.94, P < 0.01). The correlation coefficient of CO between both methods was r = 0.91 (P < 0.01). There was no significant difference in CO measured by each method at rest as well as at each work rate. The difference in CO between each method was greater at lower CO than at higher CO. At 90% of VO2max, the CO measured by acetylene rebreathing was nearly identical to that measured by the Fick method. It can be concluded that acetylene rebreathing for measurement of CO is valid not only at rest but also during exercise, especially during high-intensity exercise.
在高强度运动期间使用乙炔再呼吸法估算心输出量（CO），其可能受乙炔再循环的影响，尚未得到验证。本研究旨在使用直接Fick法验证乙炔再呼吸法在高强度运动期间测量CO的有效性。通过直接Fick法和乙炔再呼吸法在9名受试者静息时以及运动强度为其最大摄氧量（VO2max）的25%、50%、75%和90%时测量CO。通过乙炔再呼吸法测量的CO与工作率相关（r = 0.90，P < 0.01），与摄氧量相关（r = 0.94，P < 0.01）。两种方法测量的CO的相关系数为r = 0.91（P < 0.01）。在静息时以及每个工作率下，每种方法测量的CO均无显著差异。在较低CO时，每种方法之间的CO差异大于较高CO时。在VO2max的90%时，通过乙炔再呼吸法测量的CO与通过Fick法测量的几乎相同。可以得出结论，乙炔再呼吸法测量CO不仅在静息时有效，在运动期间也有效，尤其是在高强度运动期间。
