Cegla U H, Bautz M, Fröde G, Werner T
Hufeland-Klinik, Zentrum für Pneumologie und Allergologie, Bad Erns.
Pneumologie. 1997 Feb;51(2):129-36.
In a randomized prospective study in 90 patients with COAD and tracheo-bronchial instability 3 groups were formed. Group 1: Therapy as group 3+ Physiotherapy with VRP1 Desitin, Group 2: Therapy as group 3+ Physiotherapy with RC-Cornet, Group 3:
daily 40 mg prednisolon i.v., 2 x theophylline i.v. in relation to serum levels and 3 x inhalation of beta 2+ parasympathicolytic with a compressor inhaler. Therapy group 1 and 2 received the same drug and inhalation therapy as the controls. Controls of lung function before and after physiotherapy and visual analog scales for dyspnoea, cough, sputum and acceptance of the physiotherapy were performed at days 1, 4 and 7. With RC-Cornet the residual volume decreases statistically significant in comparison to VRP1 Desitin. Hyperventilation is also statistically significant smaller in RC-Cornet compared to VRP1 Desitin. The subjective improvement of sputum, dyspnoea and acceptance of the method of physiotherapy was statistically significant better for RC-Cornet. Regarding cough the significance was just failed by p < 0.055. RC-Cornet is a comfortable, effective, small accepted tool for the long term physiotherapy of patients with COAD and tracheobronchial instability.
在一项针对90例慢性阻塞性肺疾病（COAD）合并气管支气管不稳定患者的随机前瞻性研究中，分为3组。第1组：采用第3组的治疗方法+使用VRP1德西丁进行物理治疗；第2组：采用第3组的治疗方法+使用RC - 科内特进行物理治疗；第3组：
每日静脉注射40毫克泼尼松龙，根据血清水平静脉注射2次茶碱，并用压缩雾化器进行3次β2 +抗副交感神经药物吸入治疗。治疗组1和2接受与对照组相同的药物和吸入治疗。在第1、4和7天进行物理治疗前后的肺功能检查以及关于呼吸困难、咳嗽、痰液和物理治疗接受度的视觉模拟量表评估。与VRP1德西丁相比，使用RC - 科内特时残气量有统计学意义的下降。与VRP1德西丁相比，使用RC - 科内特时过度通气在统计学上也显著减少。对于RC - 科内特，痰液、呼吸困难的主观改善以及物理治疗方法的接受度在统计学上有显著更好的效果。关于咳嗽，p值为<0.055，未达到显著差异。RC - 科内特是一种用于COAD合并气管支气管不稳定患者长期物理治疗的舒适、有效且接受度较高的工具。
