Faivre J, Grosclaude P, Launoy G, Arveux P, Raverdy N, Menegoz F, Pienkowski P, Schaffer P, Daures J P, De Vathaire F
INSERM U 351, Villejuif.
Gastroenterol Clin Biol. 1997;21(3):174-80.
The purpose of this study was to compare the incidence of digestive cancers in 9 French departments and to give an estimate of this incidence for the whole of France, based on this data.
This study focused on the 1983-1987 period. The record quality for the 9 included registries (Calvados, Côted'Or, Doubs, Haute-Garonne, Hérault, Isère, Bas-Rhin, Somme, Tarn) has been assessed by the National Committee of Registries. The crude incidence rates and those standardized according to the world population have been worked out per localization and per sex. Incidence and mortality rates per department as well as mortality rates for the whole of France have enabled the assessment of the incidence and number of new digestive cancer cases per year.
Esophagus and liver cancers are distinguished by large incidence disparities, fluctuating in a ratio of 1 to 5, and by a high sex ratio. In other localizations, incidence rates vary in a ratio of 1 to 2. The incidence rates of digestive cancers were especialy high in the Bas-Rhin department. They tended to be higher in Côte-d'Or, Doubs, Calvados and Somme, than in Haute-Garonne. Hérault and Tarn. The estimated number of digestive cancers was 30,071 in males and 19,951 in females: colorectal cancer was particularly frequent, 14,179 cases and 12,228 cases, respectively.
There are some geographical variations, from one region to another, in digestive cancer incidence in France more pronounced for esophagus and liver cancers than for other localizations. Because of its frequency, colorectal cancer represents a serious problem for public health.
本研究旨在比较法国9个省消化系统癌症的发病率，并基于这些数据估算全法国的发病率。
本研究聚焦于1983年至1987年期间。9个纳入登记处（卡尔瓦多斯省、科多尔省、杜省、上加龙省、埃罗省、伊泽尔省、下莱茵省、索姆省、塔恩省）的记录质量已由国家登记委员会评估。已计算出按部位和性别划分的粗发病率以及根据世界人口标准化后的发病率。各部门的发病率和死亡率以及全法国的死亡率有助于评估每年消化系统癌症新发病例的发病率和数量。
食管癌和肝癌的发病率差异很大，波动比例为1比5，且性别比很高。在其他部位，发病率的变化比例为1比2。下莱茵省消化系统癌症的发病率特别高。在科多尔省、杜省、卡尔瓦多斯省和索姆省，发病率往往高于上加龙省、埃罗省和塔恩省。估计男性消化系统癌症病例数为30,071例，女性为19,951例：结直肠癌尤为常见，分别为14,179例和12,228例。
法国不同地区消化系统癌症的发病率存在一些地理差异，食管癌和肝癌的差异比其他部位更为明显。由于其发病率高，结直肠癌对公共卫生构成严重问题。
