Hill G E, Whitten C W
Department of Anesthesiology, University of Nebraska Medical Center, Omaha, USA.
J Cardiothorac Vasc Anesth. 1997 May;11(3):316-21. doi: 10.1016/s1053-0770(97)90101-4.
The vascular endothelium is intimately involved in a wide variety of normal physiological processes, including coagulation/anticoagulation, the maintenance of vascular tone, and pathological processes, including reperfusion injury, inflammatory syndromes, and tumor cell metastasis. This review discusses the importance of increased adhesive molecule expression on the endothelial surface in promoting circulating inflammatory cell-endothelial adherence in inflammatory conditions, as well as the role of the vascular endothelium in reperfusion injury, altered microvascular permeability states, and atherogenesis.
血管内皮密切参与多种正常生理过程，包括凝血/抗凝、血管张力维持，以及多种病理过程，包括再灌注损伤、炎症综合征和肿瘤细胞转移。本综述讨论了在炎症状态下，内皮表面黏附分子表达增加在促进循环炎症细胞与内皮黏附中的重要性，以及血管内皮在再灌注损伤、微血管通透性改变状态和动脉粥样硬化形成中的作用。
