Arushanian E B, Chernysheva E M
Eksp Klin Farmakol. 1997 Jan-Feb;60(1):7-9.
Disorders develop in the emotional sphere in the form of increased anxiety and fear in amygdalectomized rats. The pineal hormone melatonin and diazepam (in an equal dose of 0.1 mg/kg) alleviate the state of anxiety and fear in the animals. Despite some differences in behavioral activity, the effect of the drugs appears to be similar. This suggests that melatonin possesses anxiolytic properties which may be related to its effect on the function of the limbic structures.
在杏仁核切除的大鼠中，情绪领域会出现以焦虑和恐惧增加为形式的紊乱。松果体激素褪黑素和地西泮（剂量均为0.1毫克/千克）可缓解动物的焦虑和恐惧状态。尽管行为活动存在一些差异，但药物的效果似乎相似。这表明褪黑素具有抗焦虑特性，这可能与其对边缘系统结构功能的影响有关。
