[抗焦虑药抗应激作用的时间生物学特征]
[The chronobiological characteristics of the antistressor action of anxiolytic agents].
作者信息
Arushanian E B, Beĭer E V
机构信息
Department of Pharmacology, Stavropol State Medical Academy, Russia.
出版信息
Eksp Klin Farmakol. 1998 Nov-Dec;61(6):13-6.
PMID:9929809
Abstract
Agents with anxiolytic properties, namely, the tranquilizer diazepam (0.1 mg/kg), melatonin a hormone secreted by the pineal gland (0.1 mg/kg), and the beta-adrenergic blocker anapriline (5 mg/kg), remove in a similar manner stress-induced dysrhythmia in rats. Under their effect the circadian rhythm of motor activity is normalized and adaptation shifts in the time dynamics of forced swimming are encountered.
摘要
具有抗焦虑特性的药物，即镇静剂地西泮（0.1毫克/千克）、松果体分泌的一种激素褪黑素（0.1毫克/千克）以及β-肾上腺素能阻滞剂心得安（5毫克/千克），能以类似方式消除大鼠应激诱导的心律失常。在它们的作用下，运动活动的昼夜节律恢复正常，并且在强迫游泳的时间动态中出现适应变化。
相似文献
1
[The chronobiological characteristics of the antistressor action of anxiolytic agents].[抗焦虑药抗应激作用的时间生物学特征]
Eksp Klin Farmakol. 1998 Nov-Dec;61(6):13-6.
2
[Pineal melatonin exhibits more pronounced antistressor properties than anxiolytic diazepam].松果体褪黑素比抗焦虑药地西泮具有更显著的抗应激特性。
Eksp Klin Farmakol. 2007 Nov-Dec;70(6):9-12.
3
[Tofisopam and melatonin attenuate the reorganization of circadian locomotor rhythm in rats under injection-induced stress conditions].
Eksp Klin Farmakol. 2006 Mar-Apr;69(2):14-7.
4
[The comparative effect of melatonin and diazepam on shifts in the anxiety-phobia status of rats evoked by damage to the amygdala].[褪黑素与地西泮对杏仁核损伤诱发大鼠焦虑-恐惧状态变化的比较作用]
Eksp Klin Farmakol. 1997 Jan-Feb;60(1):7-9.
5
[The participation of the dorsal hippocampus in the antianxiety action of melatonin and diazepam].[背侧海马体在褪黑素和地西泮抗焦虑作用中的参与]
Eksp Klin Farmakol. 1998 Mar-Apr;61(2):13-6.
6
[Effects of anxiolytic agents on some immunologic parameters of the stressed rats].[抗焦虑药对应激大鼠某些免疫参数的影响]
Eksp Klin Farmakol. 2003 Nov-Dec;66(6):45-7.
7
[Effects of melatonin and diazepam on the heart rate variability in normal rats and rats subjected to stress].[褪黑素和地西泮对正常大鼠及应激大鼠心率变异性的影响]
Eksp Klin Farmakol. 1997 Sep-Oct;60(5):40-3.
8
[A comparative evaluation of the antidepressive activity of different beta-adrenoblockaders].[不同β-肾上腺素能阻滞剂抗抑郁活性的比较评估]
Eksp Klin Farmakol. 1994 Jan-Feb;57(1):20-1.
9
Interaction between ethanol and diazepam in mice: chronobiological aspects.乙醇与地西泮在小鼠体内的相互作用：时间生物学方面
Pharmazie. 2005 Oct;60(10):761-4.
10
[The effect of different anxiolytics on the anxiety state occurring in rats after stopping the electrical stimulation of the dorsal hippocampus].[不同抗焦虑药对大鼠停止海马背侧电刺激后出现的焦虑状态的影响]
Eksp Klin Farmakol. 1999 Sep-Oct;62(5):7-10.
Zotero 插件