Belorusov O S, Asoian G A, Martyniuk A P
Scientific Center of Surgery, Moscow.
Khirurgiia (Mosk). 1997(2):62-7.
Transorganic oxygen preservation was used in storage of 87 cadaver kidneys. The kidneys were stored for 14 to 56 h (34 +/- 1.95 on the average). After storage, all organs were transplanted to 87 patients with chronic renal insufficiency in the terminal stage. The patients age ranged from 18 to 55 years. All recipients were divided into 3 groups according to the results of the operation. Group 1 (55 patients)-the function of the organ was restored immediately, blood creatinine normalized on the 5th-10th postoperative day; subsidiary hemodialysis was not needed. Group 2 (22 patients)-the function of the transplant was restored 14-21 days after the operation; 2 to 8 sessions of hemodialysis had to be conducted. Group 3 (10 patients)-the transplant did not function due to acute irreversible canalicular necrosis or irreversible rejection. No correlative dependence between restoration of the transplant function and the duration of storage was noted (r = 0.15). Our experience allows us to assert that transorganic oxygen perfusion can ensure long-term safe storage of cadaver kidneys.
采用跨器官氧保存法对87个尸体肾进行保存。肾脏保存14至56小时（平均34±1.95小时）。保存后，将所有器官移植给87例终末期慢性肾功能不全患者。患者年龄在18至55岁之间。根据手术结果将所有受者分为3组。第1组（55例患者）——器官功能立即恢复，术后第5至10天血肌酐恢复正常；无需辅助血液透析。第2组（22例患者）——移植肾功能在术后14至21天恢复；必须进行2至8次血液透析。第3组（10例患者）——由于急性不可逆的小管坏死或不可逆排斥反应，移植肾无功能。未发现移植肾功能恢复与保存时间之间存在相关性（r = 0.15）。我们的经验使我们能够断言，跨器官氧灌注可以确保尸体肾的长期安全保存。
