Kira S
Sangyo Igaku. 1977 May;19(3):126-31.
Personal air samplers were applied to shipyard's painters putting on gas masks during the spraying work, and the levels of toluene vapour surrounding the workers were measured. On the other hand, levels of urinary hippuric acid (metabolites of toluene) of the workers were measured, and the levels of toluene vapour inhaled were calculated from the levels of urinary hippuric acid. Then the actual removing-efficiencies of toluene vapours by the use of gas masks were estimated from these two levels (i.e., toluene vapours exposed and inhaled). The values of removing-efficiencies were found to be 65.9-98.1%. The concentrations of hippuric and methylhippuric acids in the urine of workers exposed to toluene and xylene for 3 hours, collected just after the exposure, are valuable indices of these organic solvent vapours inhaled. A minute amount of urinary methylhippuric acid can be determined by means of gas chromatography.
在喷漆作业期间,将个人空气采样器应用于戴着防毒面具的造船厂油漆工,测量工人周围甲苯蒸气的水平。另一方面,测量工人尿中马尿酸(甲苯代谢物)的水平,并根据尿中马尿酸的水平计算吸入的甲苯蒸气水平。然后根据这两个水平(即暴露的和吸入的甲苯蒸气)估算使用防毒面具对甲苯蒸气的实际去除效率。发现去除效率值为65.9 - 98.1%。暴露后立即收集的接触甲苯和二甲苯3小时的工人尿液中马尿酸和甲基马尿酸的浓度,是吸入这些有机溶剂蒸气的有价值指标。尿中微量的甲基马尿酸可用气相色谱法测定。