Angulo J C, Dehaini A, Escribano J, Sanchez-Chapado M
Department of Urology, Hospital Principe de Asturias, Universidad de Alcalá de Henares, Madrid, Spain.
Scand J Urol Nephrol. 1997 Apr;31(2):193-7. doi: 10.3109/00365599709070329.
Emphysematous pyelonephritis, bilateral or in a solitary kidney, is a life-threatening condition that requires prompt diagnosis and early intervention. Reported mortality is high, despite desperate surgical measures often ending in loss of renal unit, but medical management, possibly combined with percutaneous drainage, is sometimes successful. We report two cases of emphysematous pyelonephritis, one bilateral and one in a solitary kidney, with successful conservative management. Predisposing factors were insulin-dependent diabetes mellitus and micronodular cirrhosis secondary to chronic alcoholism. Prompt sonographic diagnosis determined the success of conservative management. Escherichia coli was identified as causal factor. In the bilateral case the clinical picture improved within 48 h after control of diabetes and broad-spectrum antibiotic treatment. For the affected solitary kidney, percutaneous drainage and ureteric catheterization were required.
双侧或单侧肾脏的气肿性肾盂肾炎是一种危及生命的疾病,需要及时诊断和早期干预。尽管采取了往往导致肾单位丧失的极端手术措施,但报告的死亡率仍然很高,不过药物治疗(可能联合经皮引流)有时是成功的。我们报告两例气肿性肾盂肾炎,一例双侧,一例单侧,采用保守治疗成功。诱发因素为胰岛素依赖型糖尿病和慢性酒精中毒继发的小结节性肝硬化。及时的超声诊断决定了保守治疗的成功。已确定大肠杆菌为致病因素。在双侧病例中,糖尿病得到控制并给予广谱抗生素治疗后48小时内临床症状改善。对于患侧的单侧肾脏,需要进行经皮引流和输尿管插管。