Rottenberg G T, Gordon I, De Bruyn R
Department of Radiology, Great Ormond Street Hospital for Children NHS Trust, London, UK.
Br J Radiol. 1997 Apr;70(832):347-50. doi: 10.1259/bjr.70.832.9166069.
The objective of this study was to examine the natural history of the multicystic dysplastic kidney and the use of sonography for follow-up studies. A retrospective study was performed on 66 children with a radiological diagnosis of multicystic kidney. The change in size demonstrated on sonograms was examined. Adequate follow-up was available on 55 children over a period of 32 months (range 2-69 months). 40/55 of the kidneys underwent a reduction in size, including 22 which were no longer detectable by ultrasound. 10/55 kidneys showed an increase in size and 5/55 showed no change. Reduction in size occurred at a mean age of 84 weeks (range 20-120 weeks). In conclusion, most multicystic kidneys undergo partial or complete involution over the first 2 years of life. The mean size of the multicystic kidney at diagnosis is a poor predictor of eventual outcome.
本研究的目的是探讨多囊性发育不良肾的自然病史以及超声检查在随访研究中的应用。对66例经放射学诊断为多囊肾的儿童进行了一项回顾性研究。检查了超声检查显示的大小变化。对55例儿童进行了为期32个月（范围2 - 69个月）的充分随访。55个肾脏中有40个体积缩小，其中22个经超声检查不再可检测到。55个肾脏中有10个体积增大，5个无变化。体积缩小发生的平均年龄为84周（范围20 - 120周）。总之，大多数多囊肾在生命的头2年经历部分或完全退化。诊断时多囊肾的平均大小并不能很好地预测最终结果。
