Vinocur L, Slovis T L, Perlmutter A D, Watts F B, Chang C H
Department of Urology, Children's Hospital of Michigan, Detroit 48201.
Radiology. 1988 May;167(2):311-5. doi: 10.1148/radiology.167.2.3282252.
Thirty cases of multicystic dysplastic kidney (MCDK) were diagnosed over 11 years. Nine patients underwent nephrectomy: three for increasing kidney size (classic MCDK) and six because of an inconclusive diagnosis (hydronephrotic MCDK). Of the remaining 21 patients, 19 were followed up for a mean of 33.5 months (range, 2-101 months). Follow-up ultrasound examinations revealed that 16 kidneys did not change in size, one decreased in size after cyst puncture, and two disappeared (one after cyst puncture). This series included one case of non-renin-producing hypertension that was controlled medically, one case of nephroblastomatosis found in the removed dysplastic kidney, and one case of pyelonephritis in the contralateral kidney. When the diagnosis of classic MCDK is made with imaging modalities, the lesion may not have to be removed unless there is growth of the mass during the 1st year of life. Nine percent of these lesions will disappear within the first 3 years of follow-up, and the authors recommend an even longer period of follow-up.
在11年期间共诊断出30例多囊性发育不良肾（MCDK）。9例患者接受了肾切除术：3例因肾脏增大（典型MCDK），6例因诊断不明确（肾积水型MCDK）。其余21例患者中，19例接受了平均33.5个月（范围2 - 101个月）的随访。随访超声检查显示，16个肾脏大小未变，1个在囊肿穿刺后缩小，2个消失（1个在囊肿穿刺后）。该系列包括1例通过药物控制的非肾素性高血压病例、1例在切除的发育不良肾脏中发现的肾母细胞瘤病病例以及1例对侧肾脏的肾盂肾炎病例。当通过影像学手段诊断为典型MCDK时，除非在生命的第1年内肿块生长，否则病变可能无需切除。这些病变中有9%会在随访的前3年内消失，作者建议进行更长时间的随访。
