Kendrick J S, Atrash H K, Strauss L T, Gargiullo P M, Ahn Y W
Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA 30341-3724, USA.
Am J Obstet Gynecol. 1997 May;176(5):991-7. doi: 10.1016/s0002-9378(97)70391-0.
Our goal was to determine whether vaginal douching was associated with ectopic pregnancy among black women and whether specific douching behaviors were associated with differences in risk.
We analyzed data from a case-control study of ectopic pregnancy conducted between October 1988 and August 1990 at a major public hospital in Atlanta, Georgia. Case subjects were 197 black women with surgically confirmed ectopic pregnancies; the control group included 882 black women who were delivered of live or stillborn infants and 237 black women who were seeking to terminate a pregnancy.
The adjusted odds ratio for ectopic pregnancy associated with ever having douched was 3.8 (95% confidence interval 1.6 to 8.9). The risk increased with increasing number of years of douching at least once per month. No douching behavior was found to be without risk; even women who douched for routine cleanliness were at increased risk of ectopic pregnancy.
Vaginal douching is a modifiable behavior that may greatly increase a woman's risk of ectopic pregnancy.
我们的目标是确定阴道灌洗是否与黑人女性宫外孕有关，以及特定的灌洗行为是否与风险差异有关。
我们分析了1988年10月至1990年8月在佐治亚州亚特兰大一家主要公立医院进行的一项宫外孕病例对照研究的数据。病例组为197名经手术确诊为宫外孕的黑人女性；对照组包括882名分娩活婴或死婴的黑人女性以及237名寻求终止妊娠的黑人女性。
与曾进行过灌洗相关的宫外孕调整比值比为3.8（95%置信区间1.6至8.9）。风险随着每月至少灌洗一次的年数增加而增加。未发现任何灌洗行为没有风险；即使是为了日常清洁而灌洗的女性，宫外孕风险也会增加。
阴道灌洗是一种可改变的行为，可能会大大增加女性宫外孕的风险。
