Motoo Y, Taga H, Yamaguchi Y, Watanabe H, Okai T, Sawabu N
Department of Internal Medicine, Kanazawa University, Japan.
Am J Chin Med. 1997;25(1):97-102. doi: 10.1142/S0192415X97000135.
Twelve patients with liver cirrhosis complaining of painful muscle cramps were treated with Niuche-Shen-Qi-Wan (TJ-107). Three patients were at the decompensated state. Muscle cramps disappeared in 4 weeks on the average after oral administration of TJ-107 in all 12 patients. During the period of TJ-107 administration, there was no significant improvement of hepatic function. One patient complained of mild epigastric discomfort after taking TJ-107, but there were no other adverse effects. Our results indicate that TJ-107 is useful for treatment of painful muscle cramps in cirrhotic patients.
12例肝硬化伴肌肉痛性痉挛的患者接受了牛车肾气丸(TJ - 107)治疗。3例患者处于失代偿期。12例患者口服TJ - 107后,肌肉痉挛平均在4周内消失。在服用TJ - 107期间,肝功能无明显改善。1例患者服用TJ - 107后出现轻度上腹部不适,但无其他不良反应。我们的结果表明,TJ - 107对治疗肝硬化患者的肌肉痛性痉挛有效。