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Toxicant-induced loss of tolerance--an emerging theory of disease?毒物诱导的耐受性丧失——一种新出现的疾病理论？
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The relative efficiency of the Hardy-Weinberg equilibrium-likelihood and the conditional on parental genotype-likelihood methods for candidate-gene association studies.哈迪-温伯格平衡似然法与基于亲本基因型似然法在候选基因关联研究中的相对效率
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一种针对多重化学物质敏感症的行为遗传学方法。

A behavior-genetic approach to multiple chemical sensitivity.

作者信息

Newlin D B

机构信息

National Institute on Drug Abuse, Intramural Research Program, Baltimore, Maryland 21224, USA.

出版信息

Environ Health Perspect. 1997 Mar;105 Suppl 2(Suppl 2):505-8. doi: 10.1289/ehp.97105s2505.

DOI:10.1289/ehp.97105s2505
PMID:9167987
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1469805/
Abstract

This report emphasizes the application of behavior-genetic designs to the study of sensitivity to toxic chemicals, and features of multiple chemical sensitivity and substance abuse that are polar opposites. The implications of these issues for future research are discussed in relation to twin, adoption, and sibling pair studies, as well as in relation to the degree to which genetically selected lines of rodents that have been developed in the alcoholism field are applicable to multiple chemical sensitivity.

摘要

本报告强调了行为遗传学设计在有毒化学物质敏感性研究中的应用，以及多重化学敏感性和物质滥用这两个极端相反特征。这些问题对未来研究的影响在双胞胎、收养和同胞配对研究的背景下进行了讨论，同时也探讨了在酗酒领域培育的经基因选择的啮齿动物品系在多大程度上适用于多重化学敏感性研究。