Newlin D B
National Institute on Drug Abuse, Intramural Research Program, Baltimore, Maryland 21224, USA.
Environ Health Perspect. 1997 Mar;105 Suppl 2(Suppl 2):505-8. doi: 10.1289/ehp.97105s2505.
This report emphasizes the application of behavior-genetic designs to the study of sensitivity to toxic chemicals, and features of multiple chemical sensitivity and substance abuse that are polar opposites. The implications of these issues for future research are discussed in relation to twin, adoption, and sibling pair studies, as well as in relation to the degree to which genetically selected lines of rodents that have been developed in the alcoholism field are applicable to multiple chemical sensitivity.
本报告强调了行为遗传学设计在有毒化学物质敏感性研究中的应用,以及多重化学敏感性和物质滥用这两个极端相反特征。这些问题对未来研究的影响在双胞胎、收养和同胞配对研究的背景下进行了讨论,同时也探讨了在酗酒领域培育的经基因选择的啮齿动物品系在多大程度上适用于多重化学敏感性研究。