Dammann H G, Saeger W, Jansen I
Med Klin. 1977 Sep 30;72(39):1590-6.
This ia a case report on a eosinophilic granulomatosis. This disease falls nunder the hypereosinophilic syndrome as well as the eosinophilic leukemia, the disseminated eosinophilic collagenosis, and the endocarditis fibroplastica parietalis Löffler. These diseases are characterized by cardiovascular, pulmonary, abdominal and cerebral symptoms. An increased number of eosinophilic granulocytes constitutes the obligatory hematologic feature. Eosinophilic infiltration and vasculitis especially of the small vessels in heart, lung, liver, spleen, lymphnodes, and cerebrum are typical pathological findings. The eosinophilic granulomatosis shows in addition extravascular granulomas with abundant eosinophilic granulocytes. It is assumed that the hypereosinophilic disorders result from the same basic disease. We would suggest to described this basic disease as allergic eosinophilic collagenosis. This term implies both the supposed etiology and the histologic localisation of the disorder.
这是一篇关于嗜酸性肉芽肿病的病例报告。该疾病属于高嗜酸性粒细胞综合征，以及嗜酸性粒细胞白血病、播散性嗜酸性胶原病和洛弗勒壁层心内膜炎纤维增生症。这些疾病的特征为心血管、肺部、腹部和脑部症状。嗜酸性粒细胞增多是必备的血液学特征。嗜酸性粒细胞浸润和血管炎，尤其是心脏、肺、肝脏、脾脏、淋巴结和大脑中小血管的血管炎，是典型的病理表现。嗜酸性肉芽肿病还表现为伴有大量嗜酸性粒细胞的血管外肉芽肿。据推测，高嗜酸性粒细胞疾病源于同一种基础疾病。我们建议将这种基础疾病描述为过敏性嗜酸性胶原病。该术语既包含了推测的病因，也包含了该疾病的组织学定位。
