Vogel G E, Hansen W, Goldmann F L, Kopp K F
Med Klin. 1977 Oct 7;72(40):1617-23.
Over a period of 10 months hemodialyses in 20 patients with chronic renal failure were performed with a 40% lower heparin-dose. Blood coagulation was controlled from the activated partial thromboplastin time (APTT). There were no unfavourable side-effects, also the effectivity of the hemodialyses was not changed. However, we measured a significant increase in the hemoglobin-concentration and in the packed cell volume. Bleeding from the punctures was significantly shortened.
在10个月的时间里,对20例慢性肾衰竭患者进行了肝素剂量降低40%的血液透析。通过活化部分凝血活酶时间(APTT)来控制血液凝固。没有出现不良副作用,血液透析的有效性也没有改变。然而,我们测量到血红蛋白浓度和红细胞压积显著增加。穿刺部位的出血时间明显缩短。