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沙眼衣原体的生长刺激人单核细胞U-937细胞产生白细胞介素8。

Chlamydia trachomatis growth stimulates interleukin 8 production by human monocytic U-937 cells.

作者信息

Bianchi A, Dosquet C, Henry S, Couderc M C, Ferchal F, Scieux C

机构信息

Laboratoire de Bactériologie-Virologie-Hygiène, Hôpital Saint-Louis,Université Paris VII, France.

出版信息

Infect Immun. 1997 Jun;65(6):2434-6. doi: 10.1128/iai.65.6.2434-2436.1997.

Abstract

Growth of Chlamydia trachomatis serotypes L2 and L3 in a human monocytic cell line, U-937, increased the rate of interleukin 8 (IL-8) release 100-fold. Heat-killed chlamydiae induced a 10-fold-lower level of production of IL-8. IL-8 may play an important role in the inflammatory reaction to chlamydial infection.

摘要

沙眼衣原体L2和L3血清型在人单核细胞系U-937中的生长,使白细胞介素8(IL-8)的释放速率增加了100倍。热灭活的衣原体诱导产生的IL-8水平低10倍。IL-8可能在衣原体感染的炎症反应中起重要作用。

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