Ermolaeva S, Varfolomeeva N, Belyi Y, Tartakovskii I
Gamaleya Research Institute of Epidemiology and Microbiology, Moscow, Russia.
FEMS Microbiol Lett. 1997 May 15;150(2):189-95. doi: 10.1016/s0378-1097(97)00110-9.
A mutant strain characterized by hyperproduction of a number of cell wall and supernatant proteins was isolated after N'methyl-N'-nitro-N-nitrosoguanidine treatment of Listeria monocytogenes strain NCTC10527. Several of these proteins were identified as virulence factors. When a wild-type strain was grown in the presence of activated charcoal it was shown to exhibit the same protein pattern as the isolated mutant.
在用N-甲基-N'-硝基-N-亚硝基胍处理单核细胞增生李斯特菌菌株NCTC10527后，分离出了一种以大量细胞壁蛋白和上清液蛋白超量产生为特征的突变菌株。其中几种蛋白质被鉴定为毒力因子。当野生型菌株在活性炭存在的情况下生长时，发现它表现出与分离出的突变体相同的蛋白质模式。
