十一酸对红色毛癣菌野生型及十一酸抗性突变体微分生孢子萌发的影响。

Effect of undecanoic acid on germination of microconidia of wild and undecanoic acid resistance mutant of Trichophyton rubrum.

作者信息

Das S K, Adhya S, Banerjee A B

出版信息

Mycopathologia. 1977 Sep 16;61(2):121-3. doi: 10.1007/BF00443841.

Abstract

Effects of undecanoic acid (UDA) on germination of microconidia and elongation of germ tubes in UDA sensitive (udas) wild type Trichophyton rubrum and UDA resistant (udar) mutant derived from it, were studied. UDA inhibited conidial germination of udas and udar strains at 30 microgram/ml and 120 microgram/ml respectively which were minimum inhibitory concentrations of UDA for these two strains. When spores from both udas and udar were germinated in presence of subinhibitory concentration of UDA, germ tube growth was short. The elongation of germ tubes of spores pregerminated in absence of UDA was also inhibited by dose of UDA not sufficient to inhitib germination.

摘要

研究了十一烷酸（UDA）对UDA敏感（udas）野生型红色毛癣菌及其衍生的UDA抗性（udar）突变体中微分生孢子萌发和芽管伸长的影响。UDA分别在30微克/毫升和120微克/毫升时抑制udas和udar菌株的分生孢子萌发，这是UDA对这两种菌株的最低抑菌浓度。当udas和udar的孢子在亚抑菌浓度的UDA存在下萌发时，芽管生长较短。在没有UDA的情况下预萌发的孢子的芽管伸长也受到不足以抑制萌发的UDA剂量的抑制。