Mermel L A
Department of Medicine, Brown University School of Medicine, Providence, Rhode Island, USA.
Nutrition. 1997 Apr;13(4 Suppl):2S-4S. doi: 10.1016/s0899-9007(97)00214-1.
This article defines the complex interaction between catheterized patients and invading microbial pathogens. Catheter colonization reflects significant growth of a microbe on a catheter component. Localized intravascular catheter-related infection denotes infection at the exit site, tunnel tract, or pocket, in the absence of bloodstream infection. Systemic intravascular catheter-related infection is a complication of colonization or localized infection, usually documented by invasion of the bloodstream. Catheter sepsis is a systemic infection that is difficult to define because symptoms associated with bloodstream infection caused by the most common pathogens to infect catheterized patients, coagulase-negative staphylococci, may not meet the previously published criteria of sepsis. It is hoped that the information contained here will lead to greater uniformity in the definitions used by the many investigators in this fascinating field.
本文定义了留置导管患者与入侵微生物病原体之间的复杂相互作用。导管定植反映了微生物在导管部件上的显著生长。局部血管内导管相关感染是指出口部位、隧道或囊袋处的感染，且无血流感染。全身性血管内导管相关感染是定植或局部感染的并发症，通常通过血流入侵来记录。导管败血症是一种难以定义的全身性感染，因为由感染留置导管患者的最常见病原体凝固酶阴性葡萄球菌引起的血流感染相关症状可能不符合先前公布的败血症标准。希望这里包含的信息能使这一迷人领域的众多研究者所使用的定义更加统一。
