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大麻与记忆障碍:对自由回忆和识别记忆的影响。

Marijuana and memory impairment: effect on free recall and recognition memory.

作者信息

Miller L L, McFarland D, Cornett T L, Brightwell D

出版信息

Pharmacol Biochem Behav. 1977 Aug;7(2):99-103. doi: 10.1016/0091-3057(77)90191-5.

DOI:10.1016/0091-3057(77)90191-5
PMID:918141
Abstract

The effect of marijuana on memory was evaluated by presenting two groups of 17 male volunteers with lists of repeated or nonrepeated words following administration of a single marijuana cigarette containing 14 mg delta9-THC. An immediate free recall, final free recall and recognition memory test followed. Results indicated that marijuana significantly decreased immediate and final free recall but only slightly influenced recognition memory. Rate of acquisition on the repeated lists was the same for both groups. Long term retention of encoded information was not influenced by marijuana. The shape of the serial position curves departed slightly from those reported by other investigators in that some effects of the drug on the recency portion of the curve were noted. Both internal and external intrusions were elevated under marijuana.

摘要

通过让两组各17名男性志愿者在吸食一支含14毫克δ9 - 四氢大麻酚的大麻香烟后,记忆重复或不重复的单词列表,来评估大麻对记忆的影响。随后进行即时自由回忆、最终自由回忆和识别记忆测试。结果表明,大麻显著降低了即时和最终自由回忆,但对识别记忆的影响较小。两组在重复列表上的习得率相同。编码信息的长期保留不受大麻影响。系列位置曲线的形状与其他研究者报告的略有不同,因为注意到该药物对曲线近因部分有一些影响。在大麻作用下,内部和外部干扰均增加。

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