Tomkowski W, Borowiec B, Burakowski J, Hajduk B, Filipecki S
Kliniki Chorób Wewenetrznych, Instytutu Gruźlicy i Chorób Płuc w Warszawie.
Pneumonol Alergol Pol. 1996;64 Suppl 2:166-8.
In 18 patients with proximal deep venous thrombosis (PDVT) confirmed by phlebography, no symptoms and signs of pulmonary embolism (PE) were observed. All patients were treated with nadroparin. During first 6 days of treatment in all patients perfusion lung scans were performed. 8 patients (44.4%) of all group developed lung scans positive for PE (silent PE). Period of successful treatment of PDVT was 10 days. No evidence of recurrent PE were observed during the period of treatment. We conclude that: 1. Frequency of silent PE in patients with PDVT is very high-lack of symptoms and signs of PE does not exclude the presence of PE in this group of patients. 2. In all patients with PDVT perfusion lung scan should be performed even in cases with no symptoms and signs of PE. 3. Low molecular weight heparins administered subcutaneously are effective in treatment either silent PE or PDVT.
在18例经静脉造影证实患有近端深静脉血栓形成（PDVT）的患者中，未观察到肺栓塞（PE）的症状和体征。所有患者均接受那屈肝素治疗。在治疗的前6天，对所有患者进行了肺灌注扫描。所有患者中有8例（44.4%）肺扫描显示PE阳性（无症状性PE）。PDVT的成功治疗期为10天。在治疗期间未观察到复发性PE的证据。我们得出结论：1. PDVT患者中无症状性PE的发生率非常高——缺乏PE的症状和体征并不排除该组患者存在PE。2. 对于所有PDVT患者，即使没有PE的症状和体征，也应进行肺灌注扫描。3. 皮下注射低分子量肝素对无症状性PE或PDVT的治疗均有效。
