Krzemiński Z, Majda-Stanisławska E
Zakład Mikrobiologii Lekarskiej AM w Lodzi.
Med Dosw Mikrobiol. 1996;48(3-4):111-6.
The relationship between the count of polymorphonuclear granulocytes in blood and also between the percentage of oral and pharyngeal streptococci showing antagonistic activity on the indicator strain Staphylococcus aureus 209P and the number of staphylococci in the oral cavity and pharynx were investigated. The study comprised 92 children, of both sexes, aged 4-15; among them there were 48 children with the decreased number of circulating polymorphonuclear granulocytes due to the treatment of acute lymphoblastic leukaemia (ALL). A statistically significant negative correlation between the number of polymorphonuclear granulocytes in blood and the count of oral and pharyngeal staphylococci (both coagulase-negative and coagulase-positive) in children with ALL as well as in healthy children was revealed. The Pearsons linear correlation coefficients between these parameters were r = -0.364 (p < 0.001) and r = -0.313 (p = 0.019) for the oral cavity and for the pharynx, respectively. The streptococci showing antagonistic activity had only some influence on the count of staphylococci in the oral cavity. The Pearson's linear correlation coefficient between this number and the count of staphylococci in 1 ml of saliva was r = -0.382 (p < 0.001).
研究了血液中多形核粒细胞计数、对指示菌株金黄色葡萄球菌209P表现出拮抗活性的口腔和咽链球菌百分比与口腔和咽部葡萄球菌数量之间的关系。该研究包括92名4至15岁的儿童，男女均有；其中48名儿童因急性淋巴细胞白血病（ALL）治疗导致循环多形核粒细胞数量减少。结果显示，ALL患儿和健康儿童血液中多形核粒细胞数量与口腔和咽部葡萄球菌（凝固酶阴性和凝固酶阳性）数量之间存在统计学显著的负相关。这些参数之间的皮尔逊线性相关系数，口腔部位r = -0.364（p < 0.001），咽部r = -0.313（p = 0.019）。表现出拮抗活性的链球菌对口腔葡萄球菌数量仅有一定影响。该数量与每毫升唾液中葡萄球菌数量之间的皮尔逊线性相关系数为r = -0.382（p < 0.001）。
