Krzemiński Z, Majda-Stanisławska E
Zakład Mikrobiologii Lekarskiej Akademii Medycznej w Lodzi.
Pediatr Pol. 1996 Apr;71(4):307-11.
The frequency of isolation and the number of staphylococci and Gram-negative enteric rods in saliva were estimated in a group of 48 children of both sexes, aged 4-15 who were in the course of treatment of acute lymphoblastic leukemia (ALL). The results were compared with the same parameters in a group of 44 healthy children of the same age. Staphylococci (both coagulase-negative and coagulase-positive) were found in the oral cavities of all healthy children and of 91.6% children with ALL. However, the diseased children harbouring staphylococci revealed a significantly higher average number of these bacteria than healthy children; the respective values were 3.59 and 3.02 log CFU/ml of saliva (p = 0.0148). The average number of staphylococci in saliva was in both groups of children in negative correlation with the number of polymorphonuclear granulocytes in blood. Gram-negative enteric rods were present in the oral cavities of 13.6% of healthy children and 33.3% of children with ALL (p = 0.0005), but the counts of these bacteria were comparable. The negative correlation between the number of these bacteria and the number of polymorphonuclear granulocytes in blood was not significant.
对48名4至15岁正在接受急性淋巴细胞白血病（ALL）治疗的儿童（男女均有）的唾液进行检测，估算其中葡萄球菌和革兰氏阴性肠道杆菌的分离频率及数量。将结果与44名同龄健康儿童的相同参数进行比较。在所有健康儿童以及91.6%的ALL患儿口腔中均发现了葡萄球菌（包括凝固酶阴性和凝固酶阳性）。然而，携带葡萄球菌的患病儿童口腔中这些细菌的平均数量显著高于健康儿童；唾液中每毫升的相应数值分别为3.59和3.02 log CFU/ml（p = 0.0148）。两组儿童唾液中葡萄球菌的平均数量均与血液中多形核粒细胞的数量呈负相关。13.6%的健康儿童和33.3%的ALL患儿口腔中有革兰氏阴性肠道杆菌（p = 0.0005），但这些细菌的数量相当。这些细菌的数量与血液中多形核粒细胞的数量之间的负相关性不显著。
