头高位倾斜引起的二氧化碳分压变化对经颅多普勒记录的影响。
Effect of PCO2 changes induced by head-upright tilt on transcranial Doppler recordings.
作者信息
Cencetti S, Bandinelli G, Lagi A
机构信息
Department of Internal Medicine 1. S Maria Nuova Hospital, Florence, Italy.
出版信息
Stroke. 1997 Jun;28(6):1195-7. doi: 10.1161/01.str.28.6.1195.
BACKGROUND AND PURPOSE
Transcranial Doppler (TCD) monitoring of mean blood flow velocity (mV) during head-upright tilt can allow testing of cerebral autoregulation. Nonetheless, head-upright tilt can induce changes in the ventilation-perfusion relationship and/or respiratory activity that might influence TCD data.
METHODS
Forty-eight healthy volunteers underwent monitoring of mV and end-tidal CO2 in the horizontal position and during head-upright tilt.
RESULTS
Both mV and end-tidal CO2 significantly decreased in orthostasis (P < .01). Linear regression analysis showed a significant linkage between end-tidal CO2 and mV changes (r = .83, P < .01).
CONCLUSIONS
Changes in ventilation-perfusion ratio and in the respiratory pattern induced by head-upright tilt can significantly influence TCD data by determining a PCO2 decrease.
背景与目的
头高位倾斜期间经颅多普勒（TCD）监测平均血流速度（mV）可用于测试脑自动调节功能。尽管如此，头高位倾斜可引起通气-灌注关系和/或呼吸活动的变化，这可能会影响TCD数据。
方法
48名健康志愿者在平卧位和头高位倾斜期间接受了mV和呼气末二氧化碳监测。
结果
直立位时mV和呼气末二氧化碳均显著降低（P < .01）。线性回归分析显示呼气末二氧化碳与mV变化之间存在显著关联（r = .83，P < .01）。
结论
头高位倾斜引起的通气-灌注比和呼吸模式变化可通过导致PCO2降低而显著影响TCD数据。
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