Hamberg-Nyström H, van Setten G B, Fagerholm P
St. Erik's Eye Hospital and Karolinska Institutet, Stockholm, Sweden.
J Refract Surg. 1997 May-Jun;13(3):263-7. doi: 10.3928/1081-597X-19970501-12.
To evaluate the differences in epithelial wound healing following photorefractive keratectomy when performed with the Summit UV 200 LA and the VISX 20/20 excimer lasers.
Sixteen New Zealand rabbits were divided into two groups. One group was treated with the Summit laser and the other group treated with the VISX 20/20 laser. The treatment consisted of a -6.00 diopter photorefractive keratectomy with a 5-mm diameter treatment zone. Epithelial wound healing was followed by photography at 4 hour intervals for 64 hours. The length of the wound edge and the size, shape, and closure time of the wound were measured.
The median wound edge length at 4 hours was 18.3 mm for the Summit laser and 16.7 mm for the VISX laser. The median wound size at 4 hours was 22.0 mm2 for the Summit and 21.2 mm2 for the VISX. The median wound closure time was 53.4 hours for the Summit laser and 54.0 hours for the VISX laser.
There was no statistically significant difference in the epithelial healing of rabbit corneal wounds created by photorefractive keratectomy when performed with two current ophthalmic excimer lasers, the Summit UV 200 LA and the VISX 20/20.
评估使用Summit UV 200 LA准分子激光和VISX 20/20准分子激光进行准分子激光原位角膜磨镶术（PRK）后上皮伤口愈合的差异。
16只新西兰兔分为两组。一组用Summit激光治疗，另一组用VISX 20/20激光治疗。治疗包括在直径5毫米的治疗区域进行-6.00屈光度的准分子激光原位角膜磨镶术。每隔4小时拍照记录上皮伤口愈合情况，持续64小时。测量伤口边缘长度、伤口大小、形状和闭合时间。
Summit激光组4小时时伤口边缘长度中位数为18.3毫米，VISX激光组为16.7毫米。Summit激光组4小时时伤口面积中位数为22.0平方毫米，VISX激光组为21.2平方毫米。Summit激光组伤口闭合时间中位数为53.4小时，VISX激光组为54.0小时。
使用两种当前的眼科准分子激光Summit UV 200 LA和VISX 20/20进行准分子激光原位角膜磨镶术时，兔角膜伤口的上皮愈合在统计学上无显著差异。
