Yang F, O'Brien P C, Wienberg J, Ferguson-Smith M A
Department of Pathology, University of Cambridge, England, UK.
Cytogenet Cell Genet. 1997;76(3-4):159-63. doi: 10.1159/000134535.
The black muntjac (Muntiacus crinifrons) has an unusual karyotype of 2n = 8 in females and 2n = 9 in males. We have studied the evolution of this karyotype by hybridising chromosome-specific paints derived from flow-sorted chromosomes of the Chinese muntjac (M. reevesi, 2n = 46) to chromosomes of the black muntjac. The hybridisation pattern allowed us to infer chromosomal homologies between these two species. Tandem and centromeric fusions, reciprocal translocations, and insertions are involved in the reduction of the diploid number from 2n = 46 to 2n = 8, 9. The painting patterns further show complex chromosomal rearrangements in the male black muntjac which involve more than half the karyotype, including both sex chromosomes. Since early meiosis is reported to be normal without any visible inversion loops of the synaptonemal complex, the observed chromosomal rearrangements would lead to heterosynapsis and, therefore, leave a large fraction of the male black muntjac karyotype balanced between the two sexes.
黑麂（Muntiacus crinifrons）具有不寻常的核型，雌性为2n = 8，雄性为2n = 9。我们通过将源自中国麂（M. reevesi，2n = 46）流式分选染色体的染色体特异性探针与黑麂染色体杂交，研究了这种核型的进化。杂交模式使我们能够推断这两个物种之间的染色体同源性。串联融合、着丝粒融合、相互易位和插入参与了二倍体数目从2n = 46减少到2n = 8、9的过程。探针杂交模式进一步显示，雄性黑麂存在复杂的染色体重排，涉及超过一半的核型，包括两条性染色体。由于据报道早期减数分裂正常，没有任何可见的联会复合体倒位环，因此观察到的染色体重排会导致异源联会，从而使雄性黑麂核型的很大一部分在两性之间保持平衡。
