粪便α1-抗胰蛋白酶排泄是蛋白丢失性肠病的可靠筛查试验吗？
Is faecal alpha 1-antitrypsin excretion a reliable screening test for protein-losing enteropathy?
作者信息
Haeney M R, Fields J, Carter R A, Thompson R A, Asquith P
出版信息
Lancet. 1979 Dec 1;2(8153):1161-2. doi: 10.1016/s0140-6736(79)92387-0.
PMID:91891
Abstract
Estimation of alpha 1-antitrypsin in random faecal samples has been suggested as a reliable index of intestinal protein loss. There was a poor correlation between faecal alpha 1-antitrypsin concentrations and simultaneously measured faecal loss of 51Cr-albumin in twenty adults with suspected protein-losing enteropathy. This indicates that faecal alpha 1-antitrypsin estimation may not be a valid screening test for protein-losing enteropathy.
摘要
随机粪便样本中α1-抗胰蛋白酶的测定已被提议作为肠道蛋白质丢失的可靠指标。在20名疑似蛋白丢失性肠病的成年人中，粪便α1-抗胰蛋白酶浓度与同时测定的51Cr-白蛋白粪便丢失量之间的相关性较差。这表明粪便α1-抗胰蛋白酶测定可能不是蛋白丢失性肠病的有效筛查试验。
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