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新生儿动脉导管未闭修复术的高位脊髓麻醉。

High spinal anaesthesia for repair of patent ductus arteriosus in neonates.

作者信息

Williams R K, Abajian J C

机构信息

Department of Anesthesiology, University of Vermont, College of Medicine, Burlington, USA.

出版信息

Paediatr Anaesth. 1997;7(3):205-9. doi: 10.1046/j.1460-9592.1997.d01-70.x.

Abstract

General anaesthesia with high dose narcotics has traditionally been used for repair of patent ductus arteriosus (PDA) in high risk neonates. Spinal anaesthesia in infants has generally been limited to cases involving the lower abdomen and lower extremities. Regional anaesthesia for PDA repair could potentially offer a more rapid recovery and the possibility of blunting the stress response in this vulnerable group of patients. High spinal anaesthesia with tetracaine was utilized as an alternative to general anaesthesia in a series of fifteen consecutive patients. Patient demographics, medication dosages, level of anaesthesia, intraoperative and immediate postoperative data were obtained and recorded in a prospective fashion. Spinal anaesthesia was achieved in all patients. The average dose of tetracaine was 2.4 mg.kg-1. Two patients early in the series had an inadequate level and received supplemental isoflurane. The remainder of the patients received either no or minimal supplementation to the basic technique. Cardiovascular status of the group was very stable with minimal changes in blood pressure noted. Recovery was rapid. All three patients who were not intubated at the time of surgery were extubated soon after surgical repair was completed. No complications of the technique were noted. High spinal anaesthesia is a safe and effective alternative to general anaesthesia in high risk neonates. This technique may offer the advantage of a faster recovery time and a protective effect on the neonatal stress response. In addition the stability of this technique may encourage the use of higher levels of spinal anaesthesia in infants than has traditionally been used.

摘要

传统上,高剂量麻醉性镇痛药的全身麻醉一直用于高危新生儿动脉导管未闭(PDA)的修复。婴儿的脊髓麻醉通常仅限于涉及下腹部和下肢的病例。PDA修复的区域麻醉可能会使恢复更快,并有可能减轻这类脆弱患者群体的应激反应。在连续15例患者中,使用丁卡因高平面脊髓麻醉作为全身麻醉的替代方法。以前瞻性方式获取并记录患者的人口统计学资料、药物剂量、麻醉平面、术中和术后即刻的数据。所有患者均成功实施脊髓麻醉。丁卡因的平均剂量为2.4mg·kg-1。该系列早期的2例患者麻醉平面不足,接受了异氟烷补充麻醉。其余患者对基本技术未接受或仅接受了极少的补充麻醉。该组患者的心血管状态非常稳定,血压变化极小。恢复迅速。所有3例手术时未插管的患者在手术修复完成后不久即拔除气管导管。未发现该技术的并发症。高平面脊髓麻醉是高危新生儿全身麻醉的一种安全有效的替代方法。该技术可能具有恢复时间更快的优势,并对新生儿应激反应具有保护作用。此外,该技术的稳定性可能会促使在婴儿中使用比传统更高平面的脊髓麻醉。

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