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[神经氨酸酶处理鸡胚成纤维细胞对禽痘病毒吸附与繁殖的影响]

[Effect of neuraminidase treatment of chick embryo fibroblasts on the adsorption and reproduction of the fowl plague virus].

作者信息

Gendon Iu Z

出版信息

Vopr Virusol. 1977 Jul-Aug(4):429-32.

PMID:919501
Abstract

Treatment with neuraminidase (100 units/ml) of chick embryo fibroblasts in vitro only partially inhibits adsorption of fowl plague virus on these cells. Cultivation of chick embryo fibroblasts in the presence of 50 units/ml neuraminidase had no effect on the sensitivity of these cells to fowl plague virus and on the extent of virus reproductions. It is suggested that neuraminic acid which is a component of the external cell membrane is not only substance responsible for adsorption of orthomyxoviruses.

摘要

在体外,用神经氨酸酶(100单位/毫升)处理鸡胚成纤维细胞,只能部分抑制禽瘟病毒在这些细胞上的吸附。在含有50单位/毫升神经氨酸酶的情况下培养鸡胚成纤维细胞,对这些细胞对禽瘟病毒的敏感性以及病毒繁殖程度没有影响。有人提出,作为细胞膜外层成分的神经氨酸并非负责正粘病毒吸附的唯一物质。

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