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胰十二指肠切除术后胰肠吻合术的重新评估:86例报告,特别提及胰瘘发生率

Reappraisal of pancreaticojejunostomy after pancreaticoduodenectomy: a report of 86 cases with particular reference to the rate of pancreatic fistulation.

作者信息

Berdah S, Panis Y, Gleizes V, Sastre B, Valleur P

机构信息

Department of Surgery, Hôpital Ste Marguerite, Marseilles, France.

出版信息

Eur J Surg. 1997 May;163(5):365-9.

PMID:9195170
Abstract

OBJECTIVE

To report our experience of 86 patients who underwent pancreaticoduodenectomy followed by pancreaticojejunostomy, paying particular attention to the rate of fistulation.

DESIGN

Retrospective study.

SETTING

Two teaching hospitals, France.

SUBJECTS

86 patients (58 men and 28 women) who required pancreatic resection for adenocarcinomas of the head of the pancreas (n = 34), chronic pancreatitis (n = 21), cancer of the ampulla of Vater (n = 12), cancer of the distal bile duct (n = 6), or other causes (n = 13).

INTERVENTION

Pancreaticoduodenectomy followed by pancreaticojejunostomy with mucosa to mucosa suture.

RESULTS

26 patients (30%) developed complications, 9 (10%) required reoperation, and 8 (9%) died postoperatively. Pancreatic fistulas developed in 2 (2%), one of whom was successfully treated conservatively. The other was reoperated on and died on day 40.

CONCLUSION

Pancreaticojejunostomy after pancreaticoduodenectomy is safe, and the rate of fistulation compares favourably with that after pancreaticogastrostomy (2%).

摘要

目的

报告我们对86例行胰十二指肠切除术并随后行胰空肠吻合术患者的经验,尤其关注吻合口漏发生率。

设计

回顾性研究。

地点

法国两家教学医院。

研究对象

86例患者(58例男性和28例女性),因胰腺头部腺癌(n = 34)、慢性胰腺炎(n = 21)、 Vater壶腹癌(n = 12)、远端胆管癌(n = 6)或其他原因(n = 13)需要行胰腺切除术。

干预措施

胰十二指肠切除术后行胰空肠吻合术,采用黏膜对黏膜缝合。

结果

26例患者(30%)发生并发症,9例(10%)需要再次手术,8例(9%)术后死亡。2例(2%)发生胰瘘,其中1例经保守治疗成功,另1例再次手术,于术后第40天死亡。

结论

胰十二指肠切除术后行胰空肠吻合术是安全的,吻合口漏发生率与胰胃吻合术(2%)相比具有优势。

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