基因与血管疾病的发展
Genes and the development of vascular disease.
作者信息
Foy C A, Grant P J
机构信息
Unit of Molecular Vascular Medicine, Leeds General Infirmary, UK.
出版信息
Postgrad Med J. 1997 May;73(859):271-8. doi: 10.1136/pgmj.73.859.271.
Abstract
Clinical vascular disease occurs as the result of the chronic development of atherosclerosis, often with acute occlusive thrombus formation as the final event. Both atherosclerotic and thrombotic disorders are complex processes resulting from genetic and environmental interactions. We review genes currently implicated as risk factors and the approaches for identifying novel genetic risk factors.
摘要
临床血管疾病是动脉粥样硬化慢性发展的结果，通常以急性闭塞性血栓形成为最终事件。动脉粥样硬化和血栓形成紊乱都是由基因与环境相互作用导致的复杂过程。我们综述了目前被认为是风险因素的基因以及识别新型遗传风险因素的方法。
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