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The effect of long-term oestradiol implantation on bone mineral density in postmenopausal women who have undergone hysterectomy and bilateral oophorectomy.

作者信息

Wahab M, Ballard P, Purdie D W, Cooper A, Willson J C

机构信息

Department of Obstetrics and Gynaecology, Princess Royal Hospital, Hull, UK.

出版信息

Br J Obstet Gynaecol. 1997 Jun;104(6):728-31. doi: 10.1111/j.1471-0528.1997.tb11985.x.

DOI:10.1111/j.1471-0528.1997.tb11985.x
PMID:9197878
Abstract

Twelve women who had received oestradiol implantation on demand for at least 15 years following hysterectomy with bilateral oophorectomy, underwent bone densitometry of hip and spine. Bone mass of hip and spine was significantly elevated above that of both the age matched mean to a degree hitherto undocumented. This suggests that oestrogen in high doses or over a long period may produce a true anabolic effect on bone mass.

摘要

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