Baumüller A, Hoyme U, Madsen P O
Z Urol Nephrol. 1977 Aug;70(8):589-93.
The authors examined the possibilities of the treatment of bacterial prostatitis and yielded the following result: A medicament suited for the treatment of prostatitis must fulfil such chemical criteria, as they are at present to be found only in alkaline marcolids (e.g. erythromycin) and trimethoprim. Since trimehtoprim has a good spectre of action against gram-negative germs, it seems to be the suited remedy, for these pathogens are frequent and dominating in the pathogenesis of prostatitis. Gram-positive bacteria should be accessible to a therapy with erythromycin.
作者研究了治疗细菌性前列腺炎的可能性,得出以下结果:一种适用于治疗前列腺炎的药物必须符合这样的化学标准,即目前仅在碱性大环内酯类药物(如红霉素)和甲氧苄啶中能找到。由于甲氧苄啶对革兰氏阴性菌有良好的抗菌谱,它似乎是合适的药物,因为这些病原体在前列腺炎的发病机制中很常见且占主导地位。革兰氏阳性菌应该可以用红霉素进行治疗。