Kim K H, Yoon T J, Oh C W, Kim T H
Department of Dermatology, Gyeongsang National University Hospital, Korea.
J Dermatol. 1997 May;24(5):332-6. doi: 10.1111/j.1346-8138.1997.tb02800.x.
A 29-year-old Korean woman had erythematous papular patches on her face for six months. The eruptions recurred in a cyclic fashion along with her menstruation. The patient responded positively to an intradermal skin test for estrogen and showed marked improvement with the antiestrogen drug, Tamoxifen. We concluded that sensitivity to her own estrogen caused this dermatitis, that an intradermal skin test with progesterone and estrogen should be carried out routinely in patients with cyclic premenstrual flares, and that tamoxifen can be used as a specific therapy. To the best of our knowledge, this woman is the first patient with estrogen dermatitis reported in Korea.
一名29岁的韩国女性面部出现红斑丘疹性斑块已有六个月。皮疹随着月经周期反复发作。该患者对雌激素皮内皮肤试验呈阳性反应,使用抗雌激素药物他莫昔芬后症状明显改善。我们得出结论,对自身雌激素敏感导致了这种皮炎,对于月经前周期性发作的患者应常规进行孕激素和雌激素皮内皮肤试验,且他莫昔芬可作为一种特异性治疗药物。据我们所知,该女性是韩国报道的首例雌激素性皮炎患者。