[Evaluation of multidimensional screenings within prematurity-dysmaturity-preventive programs].

Evaluation of multidimensional screenings within the prematurity-dysmaturity-preventive-programmes. We estimated the PDP-programmes recommended in literature. The result is discussed together with the analysis of our 6000 investigated cases. We found, that, the published scores, using many factors and basing on multidimensional regression or discriminant analysis, give not a satisfactory result in predicting birth of a newborn with low weight. If you wish predict right 90% of all low birth weight infants, your risk group contains about 50% of all pregnant women. If you wish to have only a trifling risk group of 10% of all pregnant women, you can predict right only about 50% of all infants with low birth weight. We recommend for practice to go an other way. We find it is better for prophylaxis and therapy of the threatened premature labour to diagnose and treat special risks as placenta praevia, multiple pregnancies, hemorrhage during pregnancy, smoking and anamnestic previous prematurity. The summarizing of risk points is to our opinion of minor importance. Only pregnant women with risks, which need expansive apparatus and specialists, should be sended for a perinatal center (Rh-incompatibility, hydramnious, suspicious malformation, severe intern diseases). Especially the diagnosis and therapy of genetic defects must be carried out in a center. About the possibility with genetic diagnostic to diminute the birth of impaired children of low weight is given a particular explanation.