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癌症患儿中由罕见病原体引起的经皮中心静脉导管相关菌血症:病例报告及文献综述

Broviac catheter-related bacteraemias due to unusual pathogens in children with cancer: case reports with literature review.

作者信息

Castagnola E, Conte M, Venzano P, Garaventa A, Viscoli C, Barretta M A, Pescetto L, Tasso L, Nantron M, Milanaccio C, Giacchino R

机构信息

Department of Infectious Diseases, G. Gaslini Children's Hospital, Genoa, Italy.

出版信息

J Infect. 1997 May;34(3):215-8. doi: 10.1016/s0163-4453(97)94199-2.

Abstract

Among 102 episodes of intravenous catheter related bacteraemias documented between January 1989 and July 1996 in children receiving antineoplastic chemotherapy or bone marrow transplantation at G. Gaslini Children's Hospital, Genoa, Italy, were identified seven episodes due to unusual pathogens: Bacillus circulans, Bacillus licheniformis, Brevibacterium casei, Flavimonas oryzihabitans, Porphyromonas asaccharolytica, Comamonas acidovorans and Agrobacterium radiobacter. Susceptibility to different antibiotics of all strains are reported. In all cases catheter removal was required for culture negativization. All episodes were diagnosed in absence of granulocytopenia.

摘要

在1989年1月至1996年7月期间,意大利热那亚市G. Gaslini儿童医院对接受抗肿瘤化疗或骨髓移植的儿童进行记录的102例静脉导管相关菌血症病例中,发现了7例由罕见病原体引起的病例:环状芽孢杆菌、地衣芽孢杆菌、干酪短杆菌、栖稻黄单胞菌、不解糖卟啉单胞菌、食酸丛毛单胞菌和放射土壤杆菌。报告了所有菌株对不同抗生素的敏感性。所有病例均需拔除导管以使培养结果转阴。所有病例均在无粒细胞减少的情况下确诊。

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