Hristea A, Chiotan M, Tudose M, Mihalcu F
University Clinic of Infectious Diseases, N Gh Lupu Hospital, Bucharest, Romania.
J Infect. 1997 May;34(3):265-7. doi: 10.1016/s0163-4453(97)94451-0.
We report the case of an immunocompetent patient who has been the subject of 39 episodes of recurrent pneumococcal meningitis over a 20 year period. The recurrences of bacterial meningitis due to cerebrospinal fluid leakage and the presence of chronic sinusitis were not influenced by the surgical repair of a fistula and the repeated surgical draining interventions on suppurating chronic sinusital foci. Phenoxymethylpenicillin treatment reduced the number of recurrences and the combination of pneumococcal vaccine and penicillin prophylaxis allowed a 5 year period free of any recurrences.