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白色念珠菌中一个编码与热休克蛋白70（Hsp70）家族相关蛋白质的基因（SSB1）的分子克隆。

Molecular cloning of a Candida albicans gene (SSB1) coding for a protein related to the Hsp70 family.

作者信息

Maneu V, Cervera A M, Martinez J P, Gozalbo D

机构信息

Department de Microbiología y Ecología, Facultad de Farmacia, Universitat de València, Spain.

出版信息

Yeast. 1997 Jun 15;13(7):677-81. doi: 10.1002/(SICI)1097-0061(19970615)13:7<677::AID-YEA131>3.0.CO;2-6.

DOI:10.1002/(SICI)1097-0061(19970615)13:7<677::AID-YEA131>3.0.CO;2-6
PMID:9200817
Abstract

We have cloned and sequenced a Candida albicans gene (SSB1) encoding a potential member of the heat-shock protein seventy (hsp70) family. The protein encoded by this gene contains 613 amino acids and shows a high degree (85%) of sequence identity to the ssb subfamily (ssb1 and ssb2) of the Saccharomyces cerevisiae hsp70 family. The transcribed mRNA (2.1 kb) is present in similar amounts both in yeast and germ tube cells of C. albicans.

摘要

我们已经克隆并测序了白色念珠菌的一个基因（SSB1），该基因编码热休克蛋白70（hsp70）家族的一个潜在成员。该基因编码的蛋白质含有613个氨基酸，与酿酒酵母hsp70家族的ssb亚家族（ssb1和ssb2）具有高度（85%）的序列同一性。转录的mRNA（2.1 kb）在白色念珠菌的酵母细胞和芽管细胞中的含量相似。

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