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Treatment of childhood lymphangiomas with interferon-alpha.

作者信息

Reinhardt M A, Nelson S C, Sencer S F, Bostrom B C, Kurachek S C, Nesbit M E

机构信息

Department of Pediatrics, University of Minnesota Hospitals and Clinics, Minneapolis, USA.

出版信息

J Pediatr Hematol Oncol. 1997 May-Jun;19(3):232-6. doi: 10.1097/00043426-199705000-00010.

DOI:10.1097/00043426-199705000-00010
PMID:9201146
Abstract

PURPOSE

Nonsurgical treatment of lymphangiomas has shown limited efficacy and often carries unacceptable toxicities, demonstrating the need for a more effective, less toxic therapy.

PATIENTS AND METHODS

We describe two patients with lymphangiomatosis treated for 12 to 40 months with recombinant interferon-alpha.

RESULTS

Both patients demonstrated stabilization or marked improvement of disease, based on clinical and radiologic findings, with minimal toxicity.

CONCLUSIONS

The favorable responses to interferon-alpha therapy in these two cases suggest that this is an effective and well-tolerated treatment for lymphangiomas in children.

摘要

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