Torres M A, Lobo N F, Sato K, Queiroz S de S
Divisão do Grupo de Pesquisa do Núcleo de Nutrição, Centro de Referência de Saúde da Mulher, Nutrição Alimentação e Desenvolvimento Infantil da Secretaria de Saúde de São Paulo, SP-Brasil.
Rev Saude Publica. 1996 Aug;30(4):350-7. doi: 10.1590/s0034-89101996000400008.
The effectiveness of the use of chelate amino acid iron fortified fluid milk in the treatment of iron deficiency in children under four years of age was studied. The 269 children included in this trial received 1 liter/day of fluid milk fortified with 3 mg of chelate amino acid iron and were evaluated at six monthly intervals. At the beginning of the study 62.3% of the children presented anemia. After 6 months, this percentage had decreased to 41.8% and at the end of one year to 26.4%. The greatest decreases occurred in the groups comprising the subjects who were of 12 to 23 months of age and those under one year of age. Among the children who presented initial hemoglobin levels under 9.5 g/dl, 59.3% were free of anemia after one year of follow-up. Of those presenting initial hemoglobin levels between 9.5 and 10.9 g/dl, 66.7% recovered from their anemia. There was also greater hematological improvement in the children that ingested over 750 ml/day of fortified milk in those families that did not share the supply of supplement among their other members and in those families that had only one child under five years of age. These findings led to the conclusion that the fortification of fluid milk is a viable and effective method for the treatment of iron deficiency in pre-school children.
研究了使用螯合氨基酸铁强化液态奶治疗4岁以下儿童缺铁性贫血的有效性。本试验纳入的269名儿童每天饮用1升添加3毫克螯合氨基酸铁的液态奶，并每隔6个月进行评估。研究开始时，62.3%的儿童患有贫血。6个月后，这一比例降至41.8%，1年末降至26.4%。最大降幅出现在12至23个月龄的儿童组和1岁以下的儿童组。在初始血红蛋白水平低于9.5 g/dl的儿童中，随访1年后59.3%的儿童不再贫血。在初始血红蛋白水平在9.5至10.9 g/dl之间的儿童中，66.7%的儿童贫血得到恢复。在其他家庭成员不共享补充剂供应的家庭以及只有一名5岁以下儿童的家庭中，每天饮用超过750毫升强化牛奶的儿童血液学改善也更大。这些发现得出结论，强化液态奶是治疗学龄前儿童缺铁性贫血的一种可行且有效的方法。
