Cury Y, Teixeira C F, Farsky S H
Laboratory of Pathophysiology, Instituto Butantan, São Paulo, Brazil.
Toxicon. 1997 May;35(5):773-6. doi: 10.1016/s0041-0101(96)00183-3.
Intraplantar injection of 5 or 10 micrograms of BjV caused local edema in rats that was not affected by ablation of adrenal glands. In addition, no changes in plasma corticosterone levels were observed. Simultaneous injections of the venom into both hindpaws of normal animals, or injections made at varying intervals, resulted in local inflammatory reactions of comparable time-course development and analogous magnitude. These data might be related to an inability of the venom to evoke secretion of corticosteroids.
向大鼠足底注射5或10微克的BjV会引起局部水肿，且这种水肿不受肾上腺切除的影响。此外，未观察到血浆皮质酮水平有变化。向正常动物的双后爪同时注射毒液，或在不同间隔时间进行注射，会导致具有相似时间进程发展和类似程度的局部炎症反应。这些数据可能与毒液无法诱发皮质类固醇分泌有关。
