Shimon I, Berezin M, Hadani M, Tadmor R, Gross D, Karasik A
Institute of Endocrinology, Chaim Sheba Medical Center, Tel-Hashomer, Israel.
Isr J Med Sci. 1997 Jan;33(1):58-62.
Lymphocytic hypophysitis of the anterior pituitary is a rare autoimmune disease, invariably diagnosed either by surgical biopsy of the adenohypophysis or at autopsy. The current report describes the rapid development of hypopituitarism in a 42-year-old nulliparous woman with a large sellar mass, who did not undergo pituitary surgery. Transient regression of the sellar mass and partial improvement of the hypopituitarism was induced by treatment with corticoids. We suggest that the diagnosis of lymphocytic hypophysitis can be established clinically and that conservative treatment with corticoids should be considered prior to surgical intervention.
垂体前叶淋巴细胞性垂体炎是一种罕见的自身免疫性疾病，通常通过腺垂体手术活检或尸检来诊断。本报告描述了一名42岁未生育女性，有巨大鞍区肿块，未接受垂体手术，却迅速发生垂体功能减退。使用皮质类固醇治疗后，鞍区肿块短暂消退，垂体功能减退部分改善。我们建议，淋巴细胞性垂体炎可通过临床诊断，在手术干预前应考虑使用皮质类固醇进行保守治疗。
