Hoeyveld E M, Pelkmans M, Godefridis G, Stevens E A
Laboratorium Klinische Immunologie, Universitaire Ziekenhuizen K.U.L., Leuven België.
Acta Clin Belg. 1997;52(2):99-105. doi: 10.1080/17843286.1997.11718560.
The steady increase in anaphylactic reactions to latex medical gloves has raised increasing awareness in the medical community. Even gloves claimed to be hypo-allergenic still may contain substantial amounts of IgE-binding proteins. We have studied non-powdered latex and synthetic examination glove extracts for their allergenicity using the immunoblot technique. Protein levels varied considerably among glove extracts and the amount did not always correlate with the presence of allergenic proteins. IgE binding proteins were found in 2 of the 7 powder-free latex glove brands. Synthetic glove extracts did not contain allergens. The study demonstrates that immunoblot analysis is a useful technique in order to select gloves with a minimal risk to raise IgE antibodies.
对乳胶医用手套过敏反应的稳步增加，已在医学界引起了越来越多的关注。即使声称是低过敏性的手套，仍可能含有大量的IgE结合蛋白。我们使用免疫印迹技术研究了无粉乳胶和合成检查手套提取物的致敏性。手套提取物中的蛋白质水平差异很大，其含量并不总是与致敏蛋白的存在相关。在7个无粉乳胶手套品牌中的2个品牌中发现了IgE结合蛋白。合成手套提取物不含过敏原。该研究表明，免疫印迹分析是一种有用的技术，可用于选择引发IgE抗体风险最小的手套。
