改变杆状病毒生物杀虫剂宿主范围的前景。

Prospects for altering host range for baculovirus bioinsecticides.

作者信息

Thiem S M

机构信息

Department of Entomology, 243 Natural Science, Michigan State University, East Lansing 48824, USA.

出版信息

Curr Opin Biotechnol. 1997 Jun;8(3):317-22. doi: 10.1016/s0958-1669(97)80010-9.

DOI:10.1016/s0958-1669(97)80010-9

PMID:9206013

Abstract

Advances in the understanding of baculovirus replication and the identification of genes that affect host range set the stage for constructing recombinant baculoviruses for specific past insects. The modification of baculovirus host specificity has recently been achieved by inserting or deleting genes that affect virus replication or cellular defenses.

摘要

对杆状病毒复制的理解以及影响宿主范围的基因的鉴定取得进展，为构建针对特定害虫的重组杆状病毒奠定了基础。最近，通过插入或删除影响病毒复制或细胞防御的基因，实现了杆状病毒宿主特异性的修饰。