Lin Q, Zhao A, Zhou H
Renji Hospital, Shanghai Second Medical University.
Zhonghua Fu Chan Ke Za Zhi. 1996 Jun;31(6):351-2.
To investigate whether different number of times of immunization and different immunogens have any effect on the outcome of pregnancy in patients with history of primary habitual abortion.
38 cases of pregnant women with history of primary habitual abortion immunized with lymphocytes were analysed retrospectively.
The results showed that the successful pregnancy rate was 87.5% (14/16) in the women immunized two times and was 86.4% (19/22) in the women immunized four times. There was no significant difference between the two groups. The successful pregnancy rate was 84.2% (16/19) in women immunized with their husbands' lymphocytes and 89.5% (17/19) in women immunized with donors' lymphocytes. There was also no significant difference between the two groups.
In order to prevent hematogenous infection, active immunization could be reduced from four to two times and the immunogens may be selected from the husband or from healthy donor.
探讨不同免疫次数及不同免疫原对有原发性习惯性流产史患者妊娠结局的影响。
回顾性分析38例有原发性习惯性流产史且接受淋巴细胞免疫的孕妇。
结果显示，免疫两次的女性成功妊娠率为87.5%（14/16），免疫四次的女性成功妊娠率为86.4%（19/22）。两组之间无显著差异。用丈夫淋巴细胞免疫的女性成功妊娠率为84.2%（16/19），用供者淋巴细胞免疫的女性成功妊娠率为89.5%（17/19）。两组之间也无显著差异。
为预防血源性感染，主动免疫可从四次减至两次，免疫原可选用丈夫或健康供者的。
