Bäckström B, Cole M D, Carrott M J, Jones D C, Davidson G, Coleman K
Department of Pure and Applied Chemistry, University of Strathclyde, Glasgow, United Kingdom.
Sci Justice. 1997 Apr-Jun;37(2):91-7. doi: 10.1016/S1355-0306(97)72153-1.
A rapid method is described for the analysis of Cannabis products by supercritical fluid chromatography (SFC) coupled to atmospheric pressure chemical ionization-mass spectroscopic (APCI-MS) detection. The method had a shorter analysis time than GC-MS methods, without the need for derivatization prior to analysis. It was also faster than HPLC methods, with better resolution and definitive identification. Linearity of detector response to cannabidiol, delta 8-tetrahydrocannabinol, delta 9-tetrahydrocannabinol and cannabinol was established, the detection limits for mass on column being 0.55 ng, 1.20 ng, 0.69 ng and 2.10 ng respectively. The technique offers a means by which Cannabis products can be definitively identified in a single chromatographic run. Application to casework samples is described.
描述了一种通过超临界流体色谱（SFC）与大气压化学电离质谱（APCI-MS）检测联用分析大麻产品的快速方法。该方法的分析时间比气相色谱-质谱（GC-MS）方法短，分析前无需衍生化。它也比高效液相色谱（HPLC）方法更快，具有更好的分辨率和明确的鉴定结果。建立了检测器对大麻二酚、δ8-四氢大麻酚、δ9-四氢大麻酚和大麻酚的响应线性，柱上质量检测限分别为0.55 ng、1.20 ng、0.69 ng和2.10 ng。该技术提供了一种在单次色谱运行中就能明确鉴定大麻产品的方法。还描述了该方法在实际案件样本中的应用。
