Potts A J, Bennett P J, Kennedy S H, Vaccarino F J
University of Toronto.
Can J Exp Psychol. 1997 Mar;51(1):57-60. doi: 10.1037/1196-1961.51.1.57.
Previous studies have reported elevated taste thresholds in depressed subjects, but those studies did not control for changes in response bias. The current study used signal detection analyses to address this shortcoming. Sucrose detection thresholds were measured (1) in subjects with high and low Hamilton Depression Rating Scale (HAM-D) scores who did not meet standard criteria for current Major Depressive Episode (MDE); and (2) in subjects who did fulfil standard criteria for MDE. Subjects with low HAM-D scores produced significantly more false alarms than the other two groups, but taste sensitivity, as indexed by d', did not vary significantly across groups. These results suggest that changes in response bias underlie previously reported increases in sucrose taste thresholds in depressed subjects.
以往的研究报告称，抑郁症患者的味觉阈值升高，但这些研究没有对反应偏向的变化进行控制。本研究采用信号检测分析来弥补这一不足。测量了（1）汉密尔顿抑郁量表（HAM-D）得分高和低且不符合当前重度抑郁发作（MDE）标准的受试者的蔗糖检测阈值；以及（2）符合MDE标准的受试者的蔗糖检测阈值。HAM-D得分低的受试者比其他两组产生了明显更多的误报，但以d'为指标的味觉敏感性在各组之间没有显著差异。这些结果表明，反应偏向的变化是先前报道的抑郁症患者蔗糖味觉阈值升高的基础。
