Hamid A, Hume W R
Department of Restorative Dentistry, University of California, San Francisco 94143-0758, USA.
Endod Dent Traumatol. 1997 Feb;13(1):1-5. doi: 10.1111/j.1600-9657.1997.tb00001.x.
The diffusion of 2-hydroxyethylmethacrylate (HEMA) and triethylene glycol dimethacrylate (TEGDMA) from light cured bonding resin-composite resin restorations through human carious dentin was investigated. Extracted human molar teeth with different degrees of caries were obtained from consenting donors. Teeth were classified into three groups according to caries severity (mild, moderate and severe) using subjective criteria. The outer carious lesions were then removed guided by a proprietary caries detector dye. Teeth with exposure of the pulp space after caries removal were excluded from the study. A polypropylene chamber was attached to the cemento-enamel junction of each tooth to contain 1 ml distilled water. Each cavity was restored with a HEMA containing bonding resin then a TEGDMA-containing resin composite. Water samples were retrieved over a time course and analyzed by high performance liquid chromatography. There was great variation between teeth in HEMA and TEGDMA permeability. The cumulative amounts released were of similar magnitude to those observed in non-carious teeth for the mild and moderately-severe groups. However, the cumulative amounts released were markedly greater in severely carious teeth than in those with moderate or mild caries.
研究了甲基丙烯酸羟乙酯（HEMA）和二甲基丙烯酸三乙二醇酯（TEGDMA）从光固化粘结树脂 - 复合树脂修复体中通过人类龋损牙本质的扩散情况。从同意捐赠的供体处获取不同龋损程度的拔除人类磨牙。根据主观标准，将牙齿按龋损严重程度分为三组（轻度、中度和重度）。然后在一种专利龋损检测染料的引导下去除外层龋损病变。去除龋损后牙髓腔暴露的牙齿被排除在研究之外。在每颗牙齿的牙骨质 - 釉质界处连接一个聚丙烯腔室，其中装有1毫升蒸馏水。每个窝洞先用含HEMA的粘结树脂修复，然后用含TEGDMA的树脂复合材料修复。在一段时间内收集水样并通过高效液相色谱法进行分析。牙齿之间HEMA和TEGDMA的渗透性差异很大。轻度和中度龋组释放的累积量与在无龋牙齿中观察到的量相似。然而，重度龋损牙齿中释放的累积量明显大于中度或轻度龋损的牙齿。
